Event:2014 NCIGT Site Visit

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Name of P41: National Center for Image Guided Therapy/ Image Guided Therapy Program (P41EB015898)

Location of Site Visit: Shapiro Boardroom, 70 Francis Street, Boston MA 02115

Day, Date: Wednesday, November 5, 2014

AMIGO Tour: Tuesday, November 4, 7:30-8:30pm

Questions will be communicated to PI: Friday, October 31, 10am (approximately)

Written responses to be emailed to SRO: Saturday November 1, 6pm (latest)


Tuesday, November 4, 2014

Tour of Facilities (1 hour)

7:15pm: Arrival at 70 Francis Street Lobby

7:20pm: Arrival at AMIGO hallway, don gear

7: 30 -7:35 PM Introduction to AMIGO Tour (Dr. Ferenc Jolesz, Director)

7:35 – 7:40 PM Welcome in AMIGO (Steven Seltzer, MD, Dept. of Radiology Chair)

7: 40 - 8: 20 PM Tour

Wednesday, November 5, 2014

Responses to Questions

8:00 – 8:30 AM Continental Breakfast

8:30 – 8:40 AM Panel introduction (10 minutes) (Dr. Manana Sukhareva, SRO and Dr. Michael Vannier, Chairperson)

8:40 – 8:50 AM Welcome (10 minutes) Dr. Betsy Nabel, BWH President

8:50 – 9:10 AM Introduction (20 minutes) Dr. Clare Tempany

9:10 – 9:45 AM TR&D 1 (35 minutes) Prostate Dr. Clare Tempany

9:45 – 10:20 AM TR&D 2 (35 minutes) Neurosurgery. Dr. Alexandra Golby

10:20 – 10:40 AM Break (20 mins)

10:40 – 11:15 AM TR&D 3 (35 minutes) Computation. Drs. William Wells, Bruno Madore

11:15 – 11:50 AM TR&D 4 (35 minutes) Guidance. Drs. Nobuhiko Hata, Jayender Jagadeesan, Ehud Schmidt

11:50 AM – 12:10 PM Service, Collaboration, Training, Dissemination. (20 minutes) Dr. Tina Kapur

12:10 – 12:50 PM Collaborative Projects (40 minutes)

1. Enabling Technologies for MRI-Guided Prostate Interventions (Dr. Greg Fischer, WPI)

2. Quantify Treatment Response in IDH1 Mutant Glioma Patients with Metabolic MRI (Dr. Bruce Rosen, MGH)

3. Comprehensive Adaptive Plan Optimization (Dr. Kristy Brock, U Michigan)

4. Neuroimage Analysis Center (Dr. Ron Kikinis, BWH)

12:50 – 1:15 PM Service Projects (20 minutes)

1. MR-guided Cervical Cancer Brachytherapy (Dr. Ehud Schmidt) (5 minutes)

2. Squamous Cell Carcinoma of the Lung:Validation of Molecular Signatures for Prognosis (Dr. Jayender Jagadeesan) (5 minutes)

3. OpenIGTLink Service to the Community (Dr. Junichi Tokuda) (10 minutes)

1:15 – 2:00 PM Lunch/Executive Session (45 minutes)

2:00 – 2:15 PM Additional Questions/Budget (15 minutes)

2:20 PM Adjourn – Site Visitors depart for hotel

Background and Preparation Materials

AMIGO Tour on Nov 4



  • Slides for Site Visit. first drafts to be discussed on Monday, October 6. 11am-12noon. Each draft should contain 3 sections: 1) statement of aim 2) update since submission 3) answers to reviewers questions. (After we receive questions on Friday October 31st, we will insert slides into each presentation that directly answer those questions.
    • Prostate
      • Aim 1.1: To propose a platform for validating novel imaging biomarkers with molecular and routine pathology. (Ehud) Media:Updates_slides_EJS.pptx
      • Aim 1.2: To investigate and validate a platform for focal cryoablation of PCa with accurate temperature mapping and motion compensation. (Junichi)File:Prostate-Aim1-2-updates.zip
      • Aim 2: To deliver an informatics solution in support of targeted prostate biopsy and focal therapy for localized prostate cancer. (Andriy) Media:Prostate-Aim2-updates-v3.ppt
    • Neuro
    • Computation
      • Aim 1: Registration algorithms for MRI and US with emphasis on uncertainty and algorithm performance (Sandy)
      • Aim 2: Technology for simultaneous US-MRI acquisition for monitoring procedures (Bruno, Matt)
    • Guidance
      • Aim 1: Develop an integrated navigation system to accurately localize the tumor and guide the surgical instrument to the optimal resection margin in presence of significant tissue deformation. (Jay) Media:Guidance-Aim1-slides-JJ.pptx
      • Aim 2: Verify the ability of active MRI-tracked metallic interventional devices to improve interventions through improved positional accuracy and improved therapy delivery (Ehud) Media:Updates_slides_EJS.pptx
  • Service and Collaboration: Media:Site_Visit_Presentation_Collaborations_and_Service.pptx

(Last site visit for reference: http://wiki.ncigt.org/index.php/Event:2009_NCIGT_Site_Visit)